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Mild/ Natural IVF

Mild stimulation or modified natural cycle, using lower doses of fertility medication than conventional IVF
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What's involved ?

Unlike conventional 'full stimulation' IVF, Mild or natural IVF is less invasive.  

The drug dosage is enough to encourage at least one follicle to develop and to promote egg growth. As in traditional IVF, once your eggs are ready an injection of hCG or GnRH agonist is given to trigger egg maturation, followed by egg collection.

To help support your body and implantation of the embryos after transfer, progesterone supplements are also given. At Harley Street Fertility Clinic we only recommend mild stimulation or modified natural cycle IVF for very few patients because of its high cancellation and very low success rates.

Is mild IVF right for me?

Modified Natural Cycle IVF may be of benefit if:

  • You are over 43 years old
  • You’ve responded very poorly to IVF stimulation
  • Your results show you have a very low AMH level

We will discuss with you whether it is something you could consider, based on your individual test results and previous treatment history. We would only recommend it as an option if we think it gives you a good chance of success.

Possible risks and disadvantages

Poor response

It’s important to remember that even with a modified approach, there is a much higher risk compared to conventional IVF that your treatment cycle will be stopped for poor response, no eggs will be collected, of failed fertilisation or embryo development.

Fewer eggs to fertilise

You will not have as many eggs to fertilise, and resulting embryos to transfer, through mild stimulation or modified natural cycle IVF compared to conventional treatment.

Fewer embryos to freeze

You are also very unlikely to get any embryos for freezing. Should your cycle be unsuccessful, it would mean starting the whole process of stimulation again.  So mild stimulation or modified natural cycle IVF isn’t something that’s suitable for every patient.
HSFC team

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We're a friendly boutique clinic with over 150 years of fertility experience amongst four of London's most renowned consultants.  All committed to finding the right pathway for you and success first time.


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